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As of early 2025, the FDA had received more than 455 adverse event reports involving compounded semaglutide and more than 320 involving compounded tirzepatide figures that the agency now cites as active justification for enforcement

This is particularly true for the retina, as it originates from neural ectoderm and connects to the brain by the optic nerve, which shares the meningeal layers of the brain

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Once eligibility and PA approval are in place, the patient can fill the prescription through their preferred pharmacy, assuming the pharmacy can process the Bridge claim and is in good standing with CMS and NCPDP